Drug Uses

Temovate cream is a topical anti-inflammatory medication that helps reduce itching, redness, and swelling associated with many skin conditions. Temovate cream is safe for virtually every skin type, and produces very little side effects.

How Taken

Apply a thin layer of Temovate cream or Ointment to the affected skin areas twice daily. Before applying this medicine, you should wash and dry the affected areas. Gently rub this medicine sparingly onto the affected areas, until it is evenly distributed. Do not cover or bandage the skin area after applying the cream or ointment. Be careful to keep it out of your eyes. If the scalp application gets into your eyes, flush your eyes with a lot of water. Follow your doctor's directions with this medicine.

Warnings/Precautions

Return to your doctor if the condition does not improve or if it gets worse. Temovate topical alone will not treat the condition if it is an infection. Temovate topical is in the FDA pregnancy category C. This means that it is not known whether Temovate topical will be harmful to an unborn baby. Do not use this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment. If it is necessary to use Temovate during pregnancy, the smallest amount possible should be applied, for the shortest time necessary to treat the condition, under the supervision of a doctor. It is not known whether Temovate passes into breast milk. Do not use Temovate topical without first talking to your doctor if you are breast-feeding a baby.

Missed Dose

Take your next dose as soon as you remember. If it is time for your next dose, skip the missed dose and go back to your regular schedule. Do not double doses.

Possible Side Effects

No serious systemic side effects are expected unless a large amount of Temovate topical is used for a long period of time. If the drug is being absorbed by the body, you may experience blurred vision, halos around lights, an irregular heartbeat, insomnia, mood changes, weight gain, or fatigue. If you experience any of these or other unusual side effects, notify your doctor. Less serious side effects are more likely to occur. You may experience some redness, blistering, burning, itching, or peeling. Continue to use Temovate topical and talk to your doctor about any side effects. Other local side effects may also occur, especially with prolonged use of Temovate topical. These may include thinning of the skin, prolonged redness, and stretch marks. Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Storage

Store it at room temperature and away from excess heat and moisture (not in the bathroom). Keep this medication in the container it came in, tightly closed, and out of reach of children. Throw away any medication that is outdated or no longer needed.

Overdose

When absorbed into the bloodstream over a prolonged period, Temovate can cause disorders such as Cushing's syndrome. If you suspect an overdose of Temovate, seek medical attention immediately.

More Information

Do not use plastic bandages, dressings, or diapers that do not allow air to circulate to the area unless your doctor directs you to do so. The use of occlusive dressings can greatly increase the amount of drug the body absorbs. If you do use an occlusive dressing, do not use it for more than 12 hours a day. Do not use other topical products on the treated area, unless otherwise directed by your doctor.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.

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Scientists have developed retinol (the alcohol form of vitamin A) for use in mainstream cosmetics to offer Retin A-like benefi ts at a lower cost and without a prescription. THE REJUVENATING PROPERTIES of retinoids (treatments containing derivatives of vitamin A) have been highly regarded for almost two decades. They help smooth wrinkles, correct pigmentation, reduce oiliness and acne, eliminate roughness and stimulate collagen production. “The major dermatological benefit of topical retinoids is that they regulate the way cells divide and the position of those dividing cells,” explains Mr. John Kulesza, director of research and development at Young Pharmaceuticals, Inc. “They can eliminate what we call ‘dysplasia’. As we grow older some skin cells being produced are not aligned in the same way as younger skin. This results in a dull complexion and is one of the things that makes older skin look older.” Tretinoin (better known as Retin A®) is the acid form and most potent derivative of vitamin A. Retinol is the alcohol form of vitamin A. It is found in animal foods such as fish oils and liver and has only recently been developed to use as an ingredient in cosmetics. “Retinol is a form of vitamin A alcohol that was not previously used as a commercial cosmetic ingredient because it was extremely unstable. In other words, it degraded easily when exposed to oxygen, light or heat and became ineffective,” says Mr. Kulesza. “These stability issues have now been better addressed and retinol has subsequently become a popular ingre-dient in cosmetics.” “In a sense, retinol is a weak form of Retin A. It will do everything that Retin A does but not as potently,” says Dr. Bernard Raskin, an associate clinical professor at UCLA. The beauty of retinol is that its use is not regulated in the same way as Retin A. Drugs, like Renova® and Retin A, contain a biologically active form of vitamin A making them prescription drugs only. Retinol is available without a prescription in over-the-counter cosmetics. The skin may not metabolize retinol as immediately as Retin A which actually has advantages. “One of the beauties of retinol is that it is an easier product to use in conjunction with other products,” says Dr. Raskin. “Retin A is problematic in that you can’t combine it with other products and it makes the skin extremely sun sensitive. Retinol is far more forgiving. You can combine it with vitamin C and glycolic acid and it doesn’t make the skin as sun sensitive. It offers many advantages in terms of ease of use and accessibility.” Retinol is now used as a major ingredient in many fading creams (to help even out pigment), anti-wrinkle creams, facial moisturizers and sunscreens. Some products combine retinol with vitamin C and glycolic ingredients. Vitamin C and glycolics each represent their own category of therapeutic agents for treatment of the skin. “Vitamin C is an antioxidant that neutralizes free radicals reversing some skin damage as well as stimulating collagen production,” says Dr. Israel Dvoretzky, clinical professor of dermatology at Yale University. “Hydroxy acids [glycolics] are like a micro peel for the skin that remove dead cells and make it easier for treatments to take effect.” “Optimally these treatments should be used together because they all do something different to contribute to rejuvenating the skin,” explains Mr. Kulesza. “You can argue that being an anti-oxidant, vitamin C may not only help protect the skin from free radicals but also inhibit oxidation of the retinoid as it diffuses into deeper layers of the epidermis, thus improving its bioavailability. Glycolics may enhance the penetration of the retinoid and the anti-oxidants and simultaneously enhance collagen production.” “I think retinoids would probably be the most effective of these treatments on their own because we know so much about them,” says Dr. Raskin. “Vitamin C is almost as effective but there are so many forms of it on the market; some of them are good and some of them aren’t. Retin A and retinol are basically the same product you’ll find bottle to bottle, company to company.” The major side effect associated with retinoid use is sensitivity to sunlight. “Retinoids are not innocuous. If you love the sun and absolutely need to go to the beach on a sunny day you shouldn’t use retinoids,” says Mr. Kulesza. “Unfortunately you will be depriving yourself of an excellent agent but using retinoids and getting a lot of sun exposure may increase the risk of sun damage to the skin.” Says Dr. Dvoretzky: “Because retinol makes the epidermis a little thinner, there is a tendency for irritation to occur in the sun after use. On top of that, the sun actually makes any retinoid less effective so it is best for patients to use retinol products only at night.” As they thin the epidermis (outer layer of the skin), retinoids can also cause dryness and irritation in some patients. “When we thin the epidermis we are reducing the barrier that keeps water inside our skin thus increasing the possibility of moisture loss,” explains Mr. Kulesza. However, as the gentlest form of topical vitamin A, retinol is a less risky alternative. “You may get a little bit of dryness and irritation with Retin A but most people don’t seem to have any problems with retinol,” says Dr. Raskin. Taking vitamin A during pregnancy can be harmful to the fetus and so, to be on the safe side, it is advisable for pregnant women to consult their physicians before using any product containing retinol.

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