Drug Uses

Elimite is used for the treatment of scabies.

How Taken

Massage the skin from the head to the soles of the feet with Elimite. 30 grams should be sufficient for an application. Wash the cream off after 8 to 14 hours. Do not apply to open cuts or wounds. This could cause too much medication to be absorbed by your body. Talk to your doctor before taking this medicine if you are breast-feeding. Elimite may pass into breast-milk.

Warnings/Precautions

Do not apply this medication to the eyes, nose, or mouth. Use water to wash it off immediately if this happens. You should avoid sexual contact with others until the infection has been cured.

Missed Dose

Elimite is applied only once so it is unlikely for you to miss a dose.

Possible Side Effects

Notify your doctor if any of the following side effects occur: itching, burning or stinging, tingling, numbness, redness, swelling, or rash.

Storage

Store at 15° to 25°C (59° to 77°F). Keep out of the reach of children.

Overdose

Excessive use of this medicine may result in increased irritation and erythema. Contact your doctor if you suspect an overdose.

More Information

To prevent reinfection, thoroughly wash all clothing, hats, bed clothes, bed linens, hair brushes, or combs that might have been previously infected.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.

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The antibacterial and antiparasitic activities of free oleanolic acid and its glucosides and glucuronides isolated from marigold (Calendula officinalis) were investigated. The MIC of oleanolic acid and the effect on bacterial growth were estimated by A600 measurements. Oleanolic acid's influence on bacterial survival and the ability to induce autolysis were measured by counting the number of cfu. Cell morphology and the presence of endospores were observed under electron and light microscopy, respectively. Oleanolic acid inhibited bacterial growth and survival, influenced cell morphology and enhanced the autolysis of Gram-positive bacteria suggesting that bacterial envelopes are the target of its activity. On the other hand, glycosides of oleanolic acid inhibited the development of L3 Heligmosomoides polygyrus larvae, the infective stage of this intestinal parasitic nematode. In addition, both oleanolic acid and its glycosides reduced the rate of L3 survival during prolonged storage, but only oleanolic acid glucuronides affected nematode infectivity. The presented results suggest that oleanolic acid and its glycosides can be considered as potential therapeutic agents.

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